
M. Iftakhar Alam, PhD
Professor
Phone:
Email: iftakhar@isrt.ac.bd
I am currently appointed as a Professor of Applied Statistics. Earlier, I obtained bachelor’s and master’s degrees in Applied Statistics from the University of Dhaka, Bangladesh. I truly started a research career as a PhD student at the School of Mathematical Sciences, Queen Mary University of London, UK, where I looked at the adaptive designs for dose-finding in early phase clinical trials under the supervision of Dr. Barbara Bogacka and Dr. D. Stephen Coad. My current research focuses on the various aspects of dose-finding in early-phase clinical trials.
Recent Publications
- Alam, M. I. and Shanto, Shantonu Islam (2022). Patient-specific dose finding in seamless phase I/II clinical trials Sequential Analysis, 1-20.
- Alam, M. I. and Sultana, Nigar (2022). Attitudes of women toward domestic violence: what matters the most? Violence and Gender 9(2), 87-95.
- Sujan, H. M. and Alam, M. I. (2022). D-optimal designs for dose finding in phase I clinical trials. Journal of Statistical Research 55(2), 313-334.
- Alam, M. I., Mansur, Mohaimen and Barman, Prianka (2021). Early childhood development in Bangladesh and its socio-demographic determinants of importance Early Child Development and Care, 1-20.
- Rahman, Rezoanoor and Alam, M. I. (2021). Stopping for efficacy in single-arm phase II clinical trials. Journal of Applied Statistics, 49(10) 2447-2466.
- Alam, M. I. and Sultana, Nigar (2021). Construction of windows for pharmacokinetic sampling. Austrian Journal of Statistics 50(5), 23-37.
- Khan, Noor M. and Alam, M. I. (2020). Early stopping in seamless phase I/II clinical trials. Pharmaceutical Statistics 20(2), 390-412.
- Alam, M. I., Coad, D. S. and Bogacka, B. (2019). Combined criteria for dose optimisation in early phase clinical trials. Statistics in Medicine 38(21), 4172-4188.
- Alam, M. I. and Sultana, Jafrin (2019). Isotonic design for phase I clinical trials: can we improve further? Austrian Journal of Statistics 48(5), 34-44.
- Alam, M. I. (2019). Assessing the inter-patient variability in the area under the concentration curve. Journal of Statistical Research 53(1), 27-44.
- Alam, M. I. and M. Mansur (2018). A dynamic stopping rule for phase I clinical trials. Biometrical Letters 55(1), 17-30.
- Moni, M. M. and M. I. Alam (2018). Patient-specific dose finding in phase I clinical trials. Journal of Applied Statistics 45(14), 2607-2618.
- Alam, M. I., B. Bogacka, and D. Stephen Coad (2017). Pharmacokinetically guided optimum adaptive dose selection in early phase clinical trials. Computational Statistics and Data Analysis 111, 183-202.
- Alam, M. I. and M. I. Hossain (2017). On performance of the 3+3 design and its modified versions for dose finding in phase I clinical trials. Journal of Data Science 15 (1), 115-128.
- Alam, M. I (2016). A comparison between the continual reassessment method and D-optimum design for dose finding in phase I clinical trials. Biometrical Letters 53 (2), 69-82.
Recent Talks
- Combined Criteria for Dose Optimisation in Early Phase Clinical Trials, 62nd ISI World Statistics Congress, 22 August 2019, Kuala Lumpur, Malaysia.
- A Comparison Between the Continual Reassessment Method and D-optimum Design for Dose Finding in Phase I Clinical Trials, 37th Annual Conference of the International Society for Clinical Biostatistics, Birmingham, UK, August 2016.
- A Constrained Optimum Adaptive Design for Dose Finding in Early Phase Clinical Trials, 35th Annual Conference of the Society for Clinical Trials, Philadelphia, Pennsylvania, USA, May 2014.
- Adaptive Dose Finding in Early Phase Clinical Trials Incorporating Pharmacokinetic Information, 34th Annual Conference of the International Society for Clinical Biostatistics, Munich, Germany, August 2013.
- Adaptive Dose Finding in Early Phase Clinical Trials Incorporating Pharmacokinetic Information, Population Optimum Design of Experiments Workshop, Eli Lilly, UK, June 2013.
- Dose Finding in Early Phase Clinical Trials Incorporating Pharmacokinetic Information, 36th Research Students’ Conference in Probability, Statistics and Social Statistics, Lancaster University, UK, March 2013
Awards
- Conference Award for Scientists, 37th Annual Meeting of the International Society for Clinical Biostatistics, Birmingham, UK, August 2016.
- Student Conference Award, 34th Annual Meeting of the International Society for Clinical Biostatistics, Munich, Germany, August 2013.
- Fazlul Huq Hall Provost Award, University of Dhaka, Bangladesh, 2004.
Currently Teaching
- AST 201: Sampling Distributions and Simulation
- AST 304: Epidemiology
- AST 330: Data Analysis Using SPSS, SAS, and Stata
Professional Affiliations
- Member, American Statistical Association, USA.
- Member, International Society for Clinical Biostatistics, Denmark.
- Member, International Statistical Institute, The Hague, The Netherlands.
- Life Member, Bangladesh Statistical Association.